Injectable NAD · Bucharest
Injectable NAD (NAD+) in Bucharest
English translation of content medically reviewed in Romanian by Dr. Claudiu Ruscu, intensive care physician (anaesthesia & intensive care)· Romanian text reviewed 20 September 2026
NAD+ is a coenzyme involved in cellular metabolism. It is given slowly, intravenously, at our clinic in Bucharest, as part of a lifestyle focused on longevity, after a medical assessment.
from 600 RON · medical assessment included · at the clinic or at home
- Certified doctors — supervised by Dr. Claudiu Ruscu, intensive care physician
- Medical assessment included before administration
- Sterile, single-use materials
- Slow, monitored administration, for comfort
- At the clinic or at home (Bucharest & Ilfov)
Hearing about NAD+ everywhere and wondering whether it's worth it? Here is, briefly and honestly, what it does — and who it suits.
Medically assessed protocol
Benefits
A role in cellular metabolism
NAD+ is a coenzyme involved in the reactions of cellular energy metabolism and in DNA repair.
Mental clarity
Many people choose NAD+ for a feeling of focus and a clear mind.
Part of a longevity routine
It is given as part of a plan discussed at the assessment, not as a stand-alone solution.
Recovery after exertion
Useful in demanding periods, physical or mental, as a moment to recharge.
Slow administration
It is given slowly (90–180 min) for the best tolerance and comfort.
A personalised protocol
You choose between 100 mg and 250 mg, depending on your goal and the medical recommendation.
IV drip or oral supplements — when each one fits
It is not “better or worse” — they have different roles. Here is the difference, stated fairly.
| IV drip | Oral supplements | |
|---|---|---|
| Absorption | Directly into the bloodstream | Variable, through digestion |
| When it fits | A one-off session, with a medical assessment | Daily intake, over the long term |
| Role | A medical procedure, personalised protocol | General support |
An IV drip does not replace a balanced lifestyle or the treatment recommended by your doctor.
Prices
Published prices, no surprises. The medical assessment is included.
NAD+ 100 mg
Slow administration · 90 min
NAD+ 250 mg
Premium longevity protocol · 120–180 min
NAD+ Longevity course
4 NAD+ 250 mg drips as a package (vs 5000 RON separately)
See the protocol in detail
Composition, duration and price for each option, plus booking:
Reviews
What our clients say
“Am avut o experiență excelentă! Profesionalismul, atenția la detalii și grija față de pacient se observă din primul moment. Perfuziile sunt personalizate în funcție de nevoile fiecăruia, iar tot procesul se desfășoară într-un mediu sigur, modern și foarte plăcut. M-am simțit în siguranță pe tot parcursul procedurii, iar după tratament am observat o îmbunătățire clară a nivelului de energie și a stării generale. Recomand cu toată încrederea această clinică tuturor celor care își doresc servicii medicale de calitate și o abordare bazată pe dovezi, nu pe compromisuri.”
Iulian“Sunt foarte mulțumită de experiența avută la Synerva. De la programare până la finalul vizitei, totul a decurs perfect. Personalul este extrem de amabil și profesionist, iar atenția la detalii face diferența. M-am simțit confortabil și bine îngrijită. Cu siguranță voi reveni și recomand cu drag!”
Madalina Elekes“Am venit pentru o perfuzie de susținere a imunității și am fost impresionata de atenția acordată fiecărui detaliu. Atmosferă plăcută, servicii impecabile și rezultate vizibile! Recomand!”
Oana Tudor“Un tratament foarte bun, m-am simțit foarte bine după aceste perfuzii. Dna Alexandra este un adevărat profesionist.”
Alina Sima“Multumesc frumos pt tot! Sunteti minunati,profesionisti si de fiecare data voi apela cu incredere!”
Soare AlinaReal patient reviews, pulled automatically from Google and shown in their original language (Romanian). Results may vary from person to person.
NAD supplements from the pharmacy or an IV drip — what to know first
The most useful thing to know before comparing: supplements sold as "NAD+" do not, as a rule, contain NAD+. They contain precursors — Therapium NAD+ has NMN and PQQ, Herboxa NAD+ has nicotinamide riboside, ubiquinol, resveratrol and BioPerine. The name on the box describes what the product aims to increase, not what is inside it.
The reason is simple: NAD+ is a large molecule, unstable in the digestive tract, which would not get through intact. That is where the logic of intravenous administration comes from — it bypasses the problem. For a daily, inexpensive background intake, a supplement with precursors can be a reasonable option; we don't sell supplements, so we have nothing to gain by saying so.
We have written about this at length, with the compositions declared by the manufacturers and their regulatory status in the EU, in NAD supplements or an IV drip. What the molecule is and where the evidence stops: NAD+ — what it is and what it does. The difference from NADH, and the contraindications: NADH and NAD+. Prices and what determines them: injectable NAD — prices in Romania.
What a NAD+ IV drip is
NAD+ (nicotinamide adenine dinucleotide) is a coenzyme naturally present in every cell, with a key role in energy metabolism. A NAD+ IV drip gives this coenzyme intravenously, slowly, straight into the bloodstream. Intravenous administration bypasses digestion; whether this translates into higher NAD+ levels inside cells is still being studied (more on this below).
At Synerva, in Bucharest, the NAD+ IV drip is chosen for cellular energy metabolism, mental clarity and general wellbeing — as part of a lifestyle geared towards longevity. The dose and how often it is given are set together with the doctor, during the assessment.
"Injectable NAD", "NAD for infusion" or a NAD+ IV drip — what it actually means
You may have searched for "injectable NAD" or "NAD for infusion" and be wondering whether it is something other than an IV drip. In short: they refer to the same route of administration — intravenous. At Synerva, in Bucharest, NAD+ is not given as a quick injection but as a slow intravenous drip (90–180 minutes), the "infusion" form in which the coenzyme reaches the bloodstream gradually.
The reason is medical: given too quickly, NAD+ can cause passing discomfort (chest pressure, nausea, flushing). A slow rate, with monitoring, gives better tolerance and comfort. So whether you searched for "injectable NAD", "NAD for infusion" or "intravenous NAD", with us it is the same procedure: a NAD+ IV drip given by medical staff, after a prior assessment.
How a session works
1. The assessment
A doctor discusses your goal, your medical history and your tolerance before administration. The assessment is included.
2. Slow administration
NAD+ is deliberately given slowly — between 90 and 180 minutes — for comfort and the best tolerance. You can relax, read or work.
3. After the session
Many people report feeling clearer and more refreshed. NAD+ is often chosen as a course, as part of a longevity routine.
Why NAD+ declines with age
The level of NAD+ in the body does not stay constant: studies suggest it declines gradually with age — some estimates indicate considerably lower levels around the age of 50 than at 20. NAD+ takes part in the energy metabolism of the mitochondria, in DNA repair and in the activity of sirtuins, proteins associated with cellular ageing.
That is exactly why NAD+ has become a central topic in the discussion about longevity. Important to remember: an IV drip does not "stop ageing" — it is, at most, one piece of a bigger picture, alongside sleep, exercise and diet.
Is NAD+ worth it, or just a trend? What the research says
We are a clinic, not a shop selling promises — so we answer honestly. NAD+ is an active field of research, not an "elixir of youth" with guaranteed effects. You will also find sceptical voices online: some researchers argue that intravenous NAD+ does not enter cells directly and that precursors (NR, NMN) might be an alternative route. It is a real debate, and we don't hide it.
What we can say responsibly: slow intravenous administration provides high bioavailability and better tolerance than a fast drip, which is why with us it takes 90–180 minutes. We position NAD+ as part of a lifestyle geared towards longevity — not as a treatment for a disease. We do not promise to cure any condition (Alzheimer's, addictions and so on) — such claims are not supported and we do not make them. If NAD+ doesn't make sense for your goal, we tell you directly at the assessment.
Safety and contraindications
The NAD+ IV drip is given only by medical staff, with monitoring, after an assessment. Precisely because it is a medical procedure, we don't do it "for anyone, at any time". Certain situations call for caution or may be a contraindication — pregnancy and breastfeeding, some heart or kidney conditions, and active cancer, which are assessed individually, at the doctor's discretion.
Given too quickly, NAD+ can cause passing discomfort (chest pressure, nausea, flushing) — which is exactly why the slow rate is deliberate. The medical assessment is not a formality: it establishes whether the protocol suits you and at what dose. Supervision is provided by an intensive care physician, the specialty that, in hospital, deals with intravenous administration every day.
NAD+ 100 mg vs 250 mg — price and how to choose the dose
The price of a NAD+ IV drip in Bucharest starts at 600 RON. At Synerva the NAD+ IV drip is available in two doses, set together with the doctor: NAD+ 100 mg (600 RON) and NAD+ 250 mg (1250 RON). The 100 mg dose is a suitable starting point for a first experience or for maintenance sessions; the 250 mg dose provides a more concentrated intake, often chosen in protocols focused on cellular energy metabolism and longevity.
For a long-term plan there is also the NAD+ Longevity course (4290 RON), a series of sessions. The recommendation on dose and frequency is made after the medical assessment — see also the details of each option in the protocols section.
What it contains and who it suits
The protocols available are NAD+ 100 mg, a good starting point, and NAD+ 250 mg, the premium longevity option. Because results with NAD+ are built over a series, not from a single session, many people choose the NAD+ Longevity course — four NAD+ 250 mg drips as a package (4290 RON compared with 5000 RON separately). The NAD+ IV drip suits people who want long-term support for their cellular energy metabolism, mental clarity and general wellbeing.
The NAD+ IV drip is not intended to treat a condition and does not replace a specialist medical consultation. It is given only by medical staff, with monitoring, after an assessment.
Frequently asked questions
How much does a NAD+ IV drip cost in Bucharest?
From 600 RON for NAD+ 100 mg at Synerva. The prices are shown above, and the medical assessment is included.
Can I have the IV drip if my veins are hard to find?
Most of the time, yes — tell us from the start, when you book. It helps a lot to drink water in the hours before and not to arrive cold: in a hydrated, warm body the veins are easier to see and feel. The cannula is usually placed on the forearm or the back of the hand, by medical staff used to finding veins. If it cannot be placed comfortably and safely, we do not keep trying with repeated needle sticks, and we discuss the right option with you.
What is NAD+?
It is a coenzyme naturally present in every cell, with a key role in energy metabolism. It is given intravenously, slowly, after a medical assessment.
How long does a NAD+ IV drip take?
Between 90 and 180 minutes, depending on the dose. It is deliberately given slowly, for the best tolerance and comfort.
How many NAD+ sessions are needed, and how often?
It depends on your goal. Because the effects build up over a series, many people choose a course of 4 sessions (the NAD+ Longevity course), followed by maintenance sessions. The exact schedule is set by the doctor at the assessment.
What will I feel during and after a NAD+ IV drip?
Slow administration is usually well tolerated. If the rate were too fast, passing sensations could occur (chest pressure, nausea, flushing) — which is why we slow it down. After the session, many people report feeling clearer and more refreshed.
Is NAD+ worth it, or is it just marketing?
NAD+ is a field still being researched, not a miracle remedy. We position it honestly, as part of a longevity routine, given slowly after an assessment — we do not promise to cure diseases. If it doesn't make sense for you, we tell you directly.
Is there "injectable NAD", or is it only given as a drip?
The terms "injectable NAD" and "NAD for infusion" refer to the same intravenous route. At Synerva, NAD+ is given as a slow drip (90–180 min), not as a quick injection — for tolerance and comfort, with medical monitoring, after an assessment.
Can the NAD+ IV drip be done at home?
Yes, a nurse can come to your home in Bucharest and Ilfov, after the same assessment. At home the drip is just as slow as at the clinic — 90–180 minutes — and if chest pressure, nausea or flushing occur, the rate is reduced. Plan your 2–3 hours without rushing.
NAD+ 100 mg or 250 mg — which should I choose?
NAD+ 100 mg (600 RON) is a suitable starting point for a first experience or for maintenance; NAD+ 250 mg (1250 RON) provides a more concentrated intake, often chosen in protocols focused on cellular energy metabolism and longevity. The right dose is set with the doctor at the assessment.
References
The studies below support the statements on mechanism, pharmacokinetics and safety on this page. They do not support a guaranteed therapeutic outcome — each one is followed by its limitation.
[1] Grant R, Berg J, Mestayer R, et al. A Pilot Study Investigating Changes in the Human Plasma and Urine NAD+ Metabolome During a 6 Hour Intravenous Infusion of NAD. Front Aging Neurosci. 2019.
randomised trial · sample: 11 · PMID 31572171
Limitation: Only 8 healthy men aged 30–55 (3 in the control group), a single infusion followed for 8 hours, with no measurement of NAD+ inside the cells and no clinical outcome. The infusion was given at a wellness centre, and two authors have links to NAD+ Research Inc. and Springfield Wellness Center.
[2] Reyna K, Heinzen G, Patel N, et al. Intravenous infusion of nicotinamide adenine dinucleotide (NAD(+)) versus nicotinamide riboside (NR): a retrospective tolerability pilot study in a real-world setting. Front Aging. 2026.
observational study · sample: 14 · PMID 41704678
Limitation: Only 6 people received NAD+, with no randomisation, and the data were extracted retrospectively from records. All authors were employees of the chain that sold the infusions (Restore Hyperwellness). The dose was 500 mg on 4 consecutive days, double Synerva's 250 mg protocol.
[3] Covarrubias AJ, Perrone R, Grozio A, et al. NAD(+) metabolism and its roles in cellular processes during ageing. Nat Rev Mol Cell Biol. 2021.
narrative review · PMID 33353981
Limitation: A narrative review, with no systematic method. The causal link between falling NAD+ and age-related diseases, and their “reversal”, comes mainly from rodent models. The review states explicitly that it is not known whether restoring NAD+ in humans is safe and beneficial. One author is a co-founder of Napa Therapeutics.
[4] Massudi H, Grant R, Braidy N, et al. Age-associated changes in oxidative stress and NAD+ metabolism in human tissue. PLoS One. 2012.
observational study · sample: 49 · PMID 22848760
Limitation: A cross-sectional study on pelvic skin from patients operated on for another reason: a single tissue, with no follow-up over time. The abstract shows only a correlation, not a magnitude such as “at 50 compared with 20”. Two authors were directors of the company NADLife.
[5] Zhu XH, Lu M, Lee BY, et al. In vivo NAD assay reveals the intracellular NAD contents and redox state in healthy human brain and their age dependences. Proc Natl Acad Sci U S A. 2015.
observational study · PMID 25730862
Limitation: A cross-sectional study, of the brain only, using a method that was new at the time of publication. The group of volunteers is small, and the exact number is not given in the abstract. It shows an association with age, not that NAD+ given from outside changes anything.
[6] Martens CR, Denman BA, Mazzo MR, et al. Chronic nicotinamide riboside supplementation is well-tolerated and elevates NAD(+) in healthy middle-aged and older adults. Nat Commun. 2018.
randomised trial · sample: 30 · PMID 29599478
Limitation: An oral precursor, not intravenous NAD+. 30 participants enrolled, only 6 weeks per arm. NAD+ was measured in blood cells, not in muscle or brain, and the physiological effects (blood pressure, arterial stiffness) were only explored.
[7] Gallagher C, Emmanuel OO NAD⁺ supplementation for anti-aging and wellness: A PRISMA-guided systematic review of preclinical and clinical evidence. Ageing Res Rev. 2026.
systematic review · PMID 41655607
Limitation: A review without a meta-analysis, written by two authors, the first of whom runs a management company for an aesthetic clinic. It also includes 80 rodent studies. The search stops in October 2025. For intravenous NAD+, the conclusion is an absence of studies, not proof that it does not work.
Other SYNERVA services
The SYNERVA clinic in Bucharest
SYNERVA — Clinic for Energy
5 Ciprian Porumbescu St., Sector 1, Bucharest
Phone: +40 738 336 633
At the clinic or at home, in Bucharest and Ilfov.
English translation of content medically reviewed in Romanian by Dr. Claudiu Ruscu, intensive care physician (anaesthesia & intensive care) · Romanian text reviewed: 20 September 2026
Book your injectable NAD
At the clinic or at home, in Bucharest and Ilfov. Medical assessment included, published prices.