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Guides13 September 202611 min read

TAD 600 and glutathione in ampoules — what it is, what the leaflet says, what to know beforehand

Anyone searching for "glutathione ampoules" quickly lands on TAD 600. We explain what the product contains, which indications the manufacturer attributes to it and where it is actually sold in Romania — because the answer to the last question matters more than the first two.

English translation of content medically reviewed in Romanian by Dr. Claudiu Ruscu, intensive care physician (anaesthesia & intensive care)· Romanian text reviewed 13 September 2026

TAD 600 and glutathione in ampoules — what it is, what the leaflet says, what to know beforehand

If you have searched for "injectable glutathione" or "glutathione ampoules", you have almost certainly come across TAD 600. This article explains what it is, and also something the shops that sell it don't tell you.

What TAD 600 is

TAD is the trade name of an injectable preparation of glutathione, made by Biomedica Foscama in Italy. The standard pack contains 10 vials of 600 mg powder and 10 ampoules of solvent, of 4 ml each.

The glutathione in the vial is a freeze-dried (lyophilised) powder — it is not ready to use. It has to be reconstituted: the solvent is drawn up, injected into the vial with the powder, mixed and given immediately, intravenously or intramuscularly. "Immediately" is not a figure of speech: reconstituted solutions are not kept.

The indications the manufacturer attributes to it

The indications you will find in the materials of the manufacturer and the distributors are medical, not cosmetic:

  • liver conditions of various causes — alcohol-related, drug-induced, metabolic;
  • a role as an antidote in poisoning;
  • neuropathy induced by chemotherapy drugs, especially cisplatin and oxaliplatin.

Note what is not on the list: skin whitening, anti-ageing, energy, general detoxification. These are exactly the uses for which the product is most often sold online.

The part you need to read

We looked into TAD 600 before writing this article. Here is what we found, put plainly:

We could not confirm that it is authorised for sale in Romanian pharmacies. You can find it in pharmacies in the Republic of Moldova. In Romania it appears in online shops — selling peptides, hyaluronic acid, "oncology products" — which are not pharmacies and do not dispense on prescription. Some of these shops make claims with no basis at all. On pages selling TAD we came across references to "vitamin B17" in an oncology context. "Vitamin B17" is amygdalin, a substance that is not a vitamin, has no proven anti-tumour effect and carries a risk of cyanide poisoning. A shop that writes something like that is not a reliable source for anything else on its page. An injectable bought online is an injectable of unknown origin. You have no way of checking the cold chain, authenticity or sterility. And in 2019, the US authority reported seven patients with adverse reactions after improperly prepared injectable glutathione, caused by high levels of endotoxins. This is not a theoretical risk.

What a "leaflet" means for an injectable product

The leaflet of an injectable answers four questions, in this order:

  • What it contains — the active substance and the amount, plus the solvent.
  • How it is prepared — for freeze-dried products, reconstitution is a step with its own rules.
  • How it is given — the route, the rate, what must not be mixed with what.
  • What can happen — contraindications and side effects.
  • With injectable glutathione, step 3 is the underestimated one. A rapid intravenous administration is different from a slow one, and the difference does not show until a reaction occurs.

    How to check whether a medicine is authorised in Romania

    You don't have to take our word for it, or the shop's. The check takes two minutes:

  • Open the Nomenclature of medicinal products for human use (the official register of authorised medicines) of the National Agency for Medicines and Medical Devices of Romania (ANMDMR), at nomenclator.anm.ro.
  • Search by trade name (for example, TAD) and, separately, by active substance (glutathione).
  • Look at the pharmaceutical form, strength and dispensing status — whether it is prescription-only.
  • If you can't find the product or aren't sure what you are looking at, ask a pharmacist before anything else. A pharmacist in an authorised pharmacy can tell you whether the product can legally be dispensed and under what conditions.
  • An online shop that sells an injectable without asking for a prescription and without being a pharmacy has not gone through any of these steps on your behalf.

    What the guidelines say about the indications on the list

    The manufacturer's list is a starting point, not a recommendation for you. It is worth knowing, for example, that for chemotherapy-induced neuropathy the guideline of the American Society of Clinical Oncology (ASCO), updated in 2020, reconfirmed that no agent is recommended for prevention, after reviewing dozens of studies.

    This does not mean that an oncologist cannot have reasons to decide otherwise in a particular case. It means that the decision is theirs — the doctor who knows your treatment — and not that of a page selling ampoules. The same goes for liver conditions: the decision belongs to your treating doctor.

    An ampoule bought online or an IV drip in a medical setting

    Ampoule bought onlineIV drip in a medical setting
    Origin of the productunknown, with no verifiable cold chainpharmaceutical-grade glutathione
    Who prepares ituncontrolled — anyone who has the ampoulemedical staff, with sterile materials
    How it is givenno control over the ratediluted, slowly
    Assessment beforehandnonehistory, allergies, medication, contraindications
    If a reaction occursnobody is prepared to treat itstaff and equipment to treat it
    What it promisesoften whitening, anti-ageing, "detoxification"nothing guaranteed

    With us, Glutathione 600 mg takes about 30 minutes and costs 250 RON, and Glutathione 1200 mg takes about 45 minutes and costs 400 RON, with the assessment included. For a series there are courses of 4 sessions: 750 RON (600 mg) and 1,200 RON (1200 mg).

    Warning signs in a shop that sells injectables

    • It does not ask for a prescription for an injectable product.
    • It is not a pharmacy — it sells supplements, cosmetics, peptides or "oncology products" alongside.
    • It makes treatment claims for serious diseases, especially in oncology.
    • It promises skin whitening or "rejuvenation" with an injectable.
    • It gives you self-injection instructions or tells you that "it can be done at home".
    • It cannot tell you who the authorised distributor is and under what conditions the product has been stored.

    Any one of them is enough not to buy.

    Why we do not use injectable glutathione for skin whitening

    Because skin whitening is one of the uses for which injectable glutathione is most often sold online, it is worth repeating: for intravenous glutathione used for whitening, the specialist literature describes serious risks — anaphylaxis and liver toxicity — and a lack of standardised dosing protocols, and the authority in the Philippines has issued a dedicated advisory on its unsafe use. We do not give it for this purpose. In detail: the truth about glutathione.

    How we work

    At Synerva we use pharmaceutical-grade glutathione, given intravenously, at a dose of 600 or 1200 mg, diluted, at the clinic or at home, by medical staff, after an assessment. We do not sell ampoules and we do not recommend self-administration.

    The difference between buying a vial and having an IV drip in a clinic is not the price. It is who is next to you if a hypersensitivity reaction occurs, and whether what is needed to treat it is there.

    Details of the protocol and prices: injectable glutathione.

    Sources

  • TAD 600 mg / 4 ml — product description — composition, reconstitution, method of administration, manufacturer.
  • FDA — adverse reactions to improperly prepared injectable glutathione — a warning about the unsafe use of injectable glutathione.
  • ANMDMR — Nomenclature of medicinal products for human use — the official list of medicines authorised in Romania.
  • Loprinzi et al., Journal of Clinical Oncology, 2020 — the ASCO guideline on the prevention and management of chemotherapy-induced neuropathy.
  • Alzahrani et al., Cureus, 2025 — a review of the efficacy and safety of glutathione for skin whitening, including the risks of intravenous administration.
  • An informative article. We do not sell TAD 600 and we do not recommend obtaining injectables from sources that are not pharmacies. Any intravenous administration is carried out by medical staff, after an assessment.

    Frequently asked questions

    What does a TAD 600 ampoule contain?
    A vial with 600 mg of glutathione as a freeze-dried powder, plus a separate ampoule with 4 ml of solvent. It is reconstituted before administration and used immediately — the prepared solution is not kept.
    Is TAD 600 available in Romanian pharmacies?
    We could not confirm that it is authorised for sale in Romanian pharmacies. It appears in pharmacies in the Republic of Moldova, and in Romania it is sold by online shops that are not pharmacies. Check with a pharmacist or in the official list of medicines before relying on what a shop says.
    What indications does injectable glutathione have, according to the manufacturer?
    Liver conditions of various causes, a role as an antidote in poisoning and chemotherapy-induced neuropathy, especially with cisplatin and oxaliplatin. Skin whitening and anti-ageing are not among them.
    Can I give myself injectable glutathione?
    No. It is an intravenous or intramuscular administration, with a risk of hypersensitivity reaction, and a product bought online has an origin and storage conditions that you cannot verify.
    How do I check whether an injectable medicine is authorised in Romania?
    Search for the trade name and the active substance in the ANMDMR Nomenclature of medicinal products for human use, at nomenclator.anm.ro, and look at the pharmaceutical form and dispensing status. If you can't find the product or aren't sure, ask a pharmacist in an authorised pharmacy before you buy.
    How much does a glutathione IV drip cost at Synerva?
    Glutathione 600 mg costs 250 RON and takes about 30 minutes; Glutathione 1200 mg costs 400 RON and takes about 45 minutes. The courses of 4 sessions cost 750 RON and 1,200 RON respectively. The medical assessment is included.
    Can I use TAD 600 for skin whitening?
    Skin whitening is not among the indications attributed by the manufacturer. For intravenous glutathione used for this purpose, the literature describes risks of anaphylaxis and liver toxicity and a lack of standardised doses, and the authority in the Philippines has issued an advisory on its unsafe use. We do not give it for this purpose.

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